A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...
Transforming Growth Factor Beta (TGF‐β) signalling pathways are integral to a wide array of cellular processes, ranging from embryonic development to tissue homeostasis and immune regulation. TGF‐β ...
As of spring 2026, a cancer drug that has spent years in clinical development as a Wnt/beta-catenin pathway blocker has been ...