The protein actin is ubiquitous and essential for life. In mammals, every cell expresses two of its forms, beta-actin and gamma-nonmuscle-actin. Despite having distinct roles, the two forms are nearly ...

Actin dynamics underlie the mechanical behaviour of eukaryotic cells by driving shape changes, migration and division. Monomeric actin (G-actin) polymerises into filamentous actin (F-actin) in a ...

Cyclase-associated proteins (CAPs) are conserved multidomain regulators that orchestrate the continuous remodelling of the actin cytoskeleton. By binding both globular (G-actin) and filamentous actin ...