Enzyme catalysis underpins virtually all biochemical processes by accelerating reaction rates through stabilisation of transition states and precise substrate orientation within the active site.

Photodynamic therapy (PDT), characterized by its non-invasive nature and precise spatiotemporal selectivity, has garnered considerable attention for its applications in tumor and anti-infection ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications. Using an advanced technique called ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Center have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

Enzymology is the study of enzymes and enzyme-catalyzed reactions. Enzymes are biological catalysts that accelerate the rate of biological reactions. They can also perform multiple reactions ...

A new method that successfully designs serine hydrolase enzymes capable of catalyzing ester hydrolysis with high efficiency, demonstrates a computational approach for creating de novo enzymes that ...

Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications. Subscribe to our newsletter for the ...