Humans generally ingest most of their required fatty acids through their diet. Still, fatty acid biosynthesis is a vital metabolic pathway. For yeasts and bacteria, it is even indispensable. Large, ...

Fatty acid biosynthesis in bacteria is a central metabolic pathway responsible for generating the lipid components of the cell membrane and for supplying acyl chains to diverse cellular processes.

Fatty acid and polyketide biosynthesis share a modular enzymatic architecture that assembles acyl building blocks into complex molecules via successive chain‐elongation and modification reactions. In ...

Researchers have been studying the transcription factor, SREBP, a critical regulator of lipid biosynthesis. Precursor SREBP proteins, located in the endoplasmic reticulum (ER) of the cell, are ...

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...