Dietary sodium restriction is a key determinant of diuretic efficacy. When dietary sodium intake is high, postdiuretic sodium retention compensates almost entirely for the loop-diuretic-induced sodium ...

Over time, the retention of sodium leads to crackles, peripheral edema, hepatomegaly with ascites, increased blood volume, and increased cardiac filling pressures. Although diuretics do not directly ...

Short-term use of loop diuretics does not appear to be associated with changes in bone mineral density, falls or fractures in postmenopausal women, according to a new report. However, prolonged use of ...

Loop diuretics increase the risk of secondary hyperparathyroidism in CKD patients, but concurrent use of thiazide diuretics attenuate that risk. Subjects on loop diuretics had a 2.4 times increased ...

Please provide your email address to receive an email when new articles are posted on . There was no link found between ever use of loop diuretics and changes in bone mineral density, falls and ...

Please provide your email address to receive an email when new articles are posted on . Increased exposure to loop diuretics preceded development of bullous pemphigoid in patients in the United ...

Loop diuretics are cornerstone therapies for the relief of congestion in patients with heart failure. By inhibiting the Na⁺‐K⁺‐2Cl⁻ cotransporter in the thick ascending limb of the loop of Henle, ...

Close to 6 million Americans live with heart failure, and each of their hospitalizations for the condition carries an average cost of $11,500, or $11 billion in total costs each year. Because no ...

For patients with chronic heart failure (HF) who have persistent congestion despite high doses of oral loop diuretics, the right way to intensify diuretics in the outpatient setting may be narrowed, ...

A higher dose of loop diuretics was associated with more rapid skeletal muscle depletion and shorter survival in patients with liver cirrhosis, independent of the severity of disease, Japanese ...

The use of loop diuretics does not appear to be associated with changes in bone mineral density, falls or fractures in postmenopausal women, according to a report in the January 26 issue of Archives ...

Loop diuretics are widely used, especially in patients with hypertension or heart failure plus renal dysfunction. Such patients are particularly susceptible to untoward drug effects. It is, therefore, ...