Malaria is a life-threatening parasitic disease to which nearly half the world’s population is at risk. Despite global efforts towards eradication, malaria remains a significant public health problem.
UCH37/UCHL5 (PF3D7_1117100), a ubiquitin hydrolase (DUB) conserved across eukaryotes, has been shown to interact with both the proteasome and the INO80 chromatin remodeling complex in human cells 1,2.