Researchers from the Icahn School of Medicine at Mount Sinai in New York have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity-a ...

RNA-based hTERT therapy may enhance telomere activity, improving lung cell health in pulmonary fibrosis (PF). Telomere dysfunction is a significant risk factor for PF, with telomerase reactivation ...

Dysfunction resulting from mitochondrial DNA mutations has been implicated in multiple human pathologies, including ...

Chen et al. construct a comprehensive immune landscape of lymphatic malformations (LMs) atlas at single-cell resolution, uncovering pro-inflammatory responses and immune dysfunction characteristic.

In most cases, the damage is linked to mutations in the OPA1 gene, which interfere with mitochondrial function (how cells make energy and stay healthy). New research led by Thomas Schwarz, Ph.D., and ...

A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...