PrPsc Protein: The Unstoppable Chain Reaction 🧬🧠
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mcat.focus on Instagram: "Witness protein misfolding with devastating consequences. Prions (PrPSc) are pathogenic isoforms of the normal cellular prion protein (PrPC). Critically, PrPSc acts as a template, inducing endogenous PrPC to undergo conformational conversion into the pathogenic PrPSc state. This self-propagating cycle leads to the accumulation of protease-resistant aggregates, causing profound neurotoxicity. As neurons die from this toxic accumulation, they leave behind microscopic vacu
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