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Understanding Limited Scleroderma (CREST Syndrome) Scleroderma is a rare autoimmune disease that causes hardening and tightening of the skin and connective tissues. The name comes from the Greek words “sclero” (hardening) and “derma” (skin). In this video, we spotlight Limited Scleroderma, also known as CREST Syndrome—a specific form of the condition. But what does CREST stand for? C – Calcinosis: Calcium deposits under the skin R – Raynaud’s: Cold-induced color changes in fingers and toes E – E
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